Brighton & Hove Albion midfielders Davy Propper and Jose Izquierdo will miss Sunday's Premier League match at Arsenal.
Propper will miss a third successive game with a hamstring injury, while winger Izquierdo is out with a knee injury.
Midfielder Beram Kayal limped off against Newcastle last week but is set to be available for the match.
Brighton manager Chris Hughton said: "Davy Propper is out running at the moment and we will keep pushing him to see if we can have him available for our last game. He's pain free at the moment and doing quite well.
"Izquierdo is the other one who will miss out."
Asked if it's a blow to have Izquierdo ruled out, Hughton said: "When anybody misses out on a squad place it's always disappointing. But it's part and parcel of the game.
"It gives an opportunity for somebody else. At this stage of the season to only have two members of the squad missing where others might have more, it's not such a bad thing.
"It's about getting your head around it and getting the best out of the players you can."
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