Brighton & Hove Albion travel to West Brom on Wednesday aiming to end a five-game winless run.
The Seagulls' last victory was in the FA Cup third round when they won 3-1 at Bournemouth.
Albion have since lost to Liverpool, Manchester United and Fulham and drawn with Watford in the Premier League, while they also drew 0-0 at home to West Brom in the FA Cup fourth round.
The fourth round replay takes place at the Hawthorns, with the winners hosting Derby in the last 16 on February 16.
The Baggies made several changes for the fourth round tie at the Amex and West Brom boss Darren Moore is likely to do the same again.
West Brom sit fourth in the Championship after a 3-2 defeat at home to Middlesbrough on Saturday. They travel to Stoke this weekend and their main focus for the remainder of the season will be returning to the Premier League.
Jacob Murphy, Stefan Johansen and Jefferson Montero all joined the Baggies on loan in the January transfer window but are ineligible for the match.
West Brom fielded a number of their younger players in the tie at the Amex and Sam Field, Rekeem Harper, Jonathan Leko, Kyle Edwards and Rayhaan Tulloch could again feature.
Likely line-up: Bond; Mears, Bartley, Adarabioyo, Townsend; Harper, Livermore, Field; Hoolahan, Leko, Robson-Kanu. Subs (from): Myhill, Gibbs, Edwards, Tulloch, Gayle, Howkins, Holgate, Dawson, Hegazi, Barry, Rodriguez, Brunt.
BRIGHTON & HOVE ALBION
Seagulls boss Chris Hughton is likely to make several changes from Saturday's 0-0 Premier League draw with Watford.
Hughton has already confirmed Iran winger Alireza Jahanbakhsh will start the match. He has not featured for the Seagulls since early November when he suffered a hamstring injury in the defeat at Everton.
Dan Burn is set to make his second Brighton appearance in central defence and left-back Bernardo is also back available after a hamstring injury.
David Button, Bruno, Leon Balogun, Beram Kayal, Anthony Knockaert and Florin Andone are also likely to come into the starting line-up.
Dale Stephens is a doubt after missing the Watford draw with a hip injury and Jose Izquierdo is still ruled out.
Likely line-up: Button; Bruno, Balogun, Burn, Bernardo; Kayal, Bissouma, Propper; Jahanbakhsh, Andone, Knockaert. Subs (from): Sanchez, Montoya, Duffy, Dunk, Bong, March, Stephens, Sanders, Gyokeres, Murray, Locadia.
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