The two clubs met in pre-season and played out a 1-1 draw, however three points are at stake this time around.
As ever, with some key games to watch out for, we preview the main talking points ahead of this weekend and Monday’s top-flight fixture list. Scroll and click through the pages:
9. Chelsea without three summer signings
While Chelsea won’t exactly be understrength, Frank Lampard has suffered a blow with three of his summer signings - Hakim Ziyech, Ben Chilwell and Thiago Silva - ruled out of Monday night’s clash. Can Brighton capitalise? Photo: GLYN KIRK
10. Not according to Michael Owen
Brighton will likely hand a debut to marquee signing Adam Lallana but former Liverpool striker Michael Owen doesn’t think that’ll be enough as he predicts Graham Potter’s men to lose 3-1 at the Amex Stadium. Photo: PAUL ELLIS