The Three Lions will face Iran, the United States and Wales in Group B as they bid to reach the final on December 18 and lift the famous trophy for the first time since 1966.
Southgate's squad announcement has been keenly-anticipated, with many key decisions still left to be made.
Defenders Reece James and Ben Chilwell will miss the finals through injury, and the England boss is sweating on the fitness of UEFA Euro 2020 heroes Kalvin Phillips and Kyle Walker.
With Southgate’s announcement mere hours away, new video game Football Manager 2023 has predicted the 26-man Three Lions squad for the tournament in the Middle East.
You can view England’s squad for the 2022 FIFA World Cup in Qatar, as predicted by Football Manager 2023, in the gallery below.
1. FIFA World Cup Qatar 2022: Football Manager 2023 predicts Gareth Southgate's 26-man England squad for the tournament in the Middle East
Gareth Southgate will announce the 26 players that will represent England at the 2022 World Cup in Qatar, which is scheduled to kick off in ten days. later today. (Photo by UEFA/UEFA via Getty Images) Photo: UEFA
2. Aaron Ramsdale (Arsenal)
The Arsenal shot-stopper has been imperious in goal for the Gunners this season, in real life and on Football Manager, which has seen him earn a place in the squad. Pic by Stu Forster - Getty Images Photo: Stu Forster
3. Jordan Pickford (Everton)
Pickford is an almost certainty for the World Cup, being England's number one for both the 2018 World Cup and Euro 2020. (Photo by Carl Recine - Pool/Getty Images) Photo: Carl Recine - Pool
4. Nick Pope (Newcastle United)
The Magpies keeper has been in scintillating form so far this season, helping Newcastle to third in the Premier League. The former Charlton Athletic and Burnley man started in goal for England's most recent fixture against Germany in September (Photo by Mike Egerton - Pool/Getty Images) Photo: Pool